The difference between "reservation" and "reservation" is tricky, and many details of New Year’s Eve dinner need to be paid attention to.

  "Pre-emptive reservation for reunion dinner" and "Hot reservation for New Year’s Eve" … … The "New Year’s Eve" launched by major hotels is extremely popular, and a table for New Year’s Eve in some hotels is hard to find. Many citizens also moved the New Year’s Eve dinner from their homes to hotels.

  At the same time, the rules and regulations of some hotels make consumers feel quite inconvenient.

  The fixed menu, limited meal time, and extra people and fees make consumers very nervous, and the difference between "booking" and "booking" New Year’s Eve is even more puzzling to consumers … …

  Ordering is too restrictive, and there is still a time limit for eating.

  Near the Spring Festival, many hotels have started the New Year’s Eve dinner mode ahead of schedule, and put up slogans such as "reunion dinner", "New Year’s Eve dinner" and "Spring Festival is not closed". Posters with delicious dishes are very attractive. Going out to the hotel for New Year’s Eve dinner is also sought after by many citizens.

  "There is only one table for the New Year’s Eve dinner now, and the rest are booked out." In a hotel near Qingnian Road, two staff members are receiving four or five consumers, who are all consulting about the New Year’s Eve dinner. The staff handed over three menus with three packages at different price points. Each set meal includes cold dishes, hot dishes and staple foods. "The dishes prepared in the package are all dishes that customers usually order and give good feedback. The dishes of the New Year’s Eve can only be ordered according to the dishes in the package."

  According to the investigation of 10 hotels, the reporter found that all the New Year’s Eve dinners provided by hotels are set meals, and it is impossible to order food at will according to personal preferences. Seven companies have limited the meal time, stipulating that the meal time for the New Year’s Eve is two hours, which is the premise of booking.

  The staff of a hotel near Panjiayuan said that the reservation for New Year’s Eve dinner is very popular, and taking two hours as the dining interval can meet the needs of more consumers to go out for New Year’s Eve dinner. The set meal is introduced in the hotel because of the large amount of orders for New Year’s Eve dinner, and the ingredients need to be prepared in advance. Some dishes with similar prices can also be exchanged individually according to the needs of guests.

  "The favorite dishes are not in a set meal yet, so it is necessary to take into account the tastes of the elderly and children. It is very nerve-racking when choosing a set meal." A consumer said that in order to choose a package that is more suitable for his family, he has not made a decision after comparing with many hotels he frequents. "When a family comes out to have a happy New Year’s Eve dinner, it always feels less comfortable because of the limitations of time and dishes."

  The package has a "head fee" disguised as a low consumption.

  The way to set up the New Year’s Eve dinner package is used by hotels, and the package price is fixed, but the number of people to eat is not clearly specified. The staff of a hotel near Changying area in Chaoyang District said that a big table can seat 10 people, as long as they can sit down and have enough food to squeeze more people.

  However, the reporter found in the survey that some hotels have also made clear the number of diners in the package. In a hotel near Wangfujing, there are 6, 8 and 10 people in various New Year’s Eve dinner packages, and children over 1.2 meters are included in the number of people eating. A hotel near the East Third Ring Road has also stipulated the number of diners for the New Year’s Eve dinner package, and each additional diner needs to increase the cost near 500 yuan.

  "Chinese New Year is a big family, even the old and the young. After the number is set, you can’t book a table because you have more than two or three people. There are several children among them, all of whom are counted. Such rules and regulations are hard to understand. " A consumer said that the purpose of the New Year’s Eve dinner is to reunite, be lively and enjoy the happy atmosphere of the whole family sitting together, and the conditions set by the merchants during the meal have discounted the significance of the New Year’s Eve dinner.

  On November 1, 2014, the Measures for the Management of Catering Industry (Trial) jointly issued by the Ministry of Commerce and the National Development and Reform Commission clearly stipulated that catering operators are prohibited from setting minimum consumption. Violators can be fined up to 30,000 yuan.

  "This is the performance of merchants setting minimum consumption in disguise. When consumers choose New Year’s Eve, they can communicate and negotiate with merchants according to relevant regulations." Liu Yang, a lawyer of Beijing Jingxi Law Firm, said that although the restaurant didn’t specify the minimum consumption per capita, it set the set meal amount and stipulated the number of diners. When the number of diners increased, it was necessary to pay the meal fee, which was suspected of setting the minimum consumption.

  remind

  "reservation" or "reservation"

  It’s best to sign the contract first.

  In the investigation, the reporter found that there are two expressions of "reservation" and "reservation" in the propaganda language played in the hotel.

  Liu Yang said that when going out to choose a New Year’s Eve hotel, we should pay attention to some merchants’ "word games" to avoid losing money. "Reservation" refers to the need to pay part of the deposit, which can be used as liquidated damages when the payer breaches the contract. After the hotel breaches the contract, it should pay double deposit as liquidated damages. The deposit in the "reservation" is not guaranteed, and it can be refunded when the schedule changes. "When choosing a New Year’s Eve hotel, consumers should sign a contract with the hotel, stipulating the dining price, time, whether they can bring their own drinks, and ‘ Deposit ’ Or ‘ Deposit ’ And other issues to avoid unpleasantness before or during meals, so that their own interests are not guaranteed. "

  Our reporter Zhao Xibin and photo

The cumulative turnover of carbon emission quotas in the target carbon market of anchoring "double carbon" was 194 million tons.

  CCTV News:On October 27th, the Ministry of Ecology and Environment released the 2022 Annual Report on China’s Policies and Actions to Address Climate Change. According to the report, since 2021, China has actively implemented the Paris Agreement, vigorously and orderly promoted various key tasks around peak carbon dioxide emissions’s carbon neutrality goal, and achieved remarkable results.

  At present, China has established the "1+N" policy system of carbon neutrality in peak carbon dioxide emissions, formulated the medium and long-term greenhouse gas emission control strategy, promoted the construction of the national carbon emission trading market, and worked out and implemented the national climate change adaptation strategy.

  According to preliminary accounting, in 2021, the carbon dioxide emission per unit GDP in China will be 3.8% lower than that in 2020 and 50.8% lower than that in 2005. Non-fossil energy accounts for 16.6% of primary energy consumption, and the total installed capacity of wind power and solar power generation will reach 635 million kilowatts, which will significantly reduce the coal consumption per unit GDP, and the forest coverage rate and stock volume will achieve "double growth" for 30 consecutive years. On the first anniversary of the launch of the national carbon emission trading market, the cumulative turnover of carbon emission quotas in the carbon market was 194 million tons, with a cumulative turnover of 8.492 billion yuan.

  It is estimated that by 2030, the carbon dioxide emission per unit GDP in China will be reduced by more than 65% compared with that in 2005, the proportion of non-fossil energy in primary energy consumption will reach about 25%, the forest stock will increase by 6 billion cubic meters compared with that in 2005, and the total installed capacity of wind power and solar power will reach more than 1.2 billion kilowatts.

The American subsidiary of Jianyou Co., Ltd. lost more than 100 million yuan in five years: the former supervisor of the company was hidden behind the merger case that year.

  As a giant heparin producer, () (SH603707, stock price 11 yuan, market value 17.77 billion yuan) once had a market value of more than 50 billion yuan at its peak, but at present its market value is only about 17.8 billion yuan, and the market value exceeding 30 billion yuan has disappeared in recent years.

  In the 2023 annual report of Jianyou Co., Ltd., the total amount of monetary funds deposited abroad was 158 million yuan, but the company checked "Not applicable" for overseas assets in the annual report.

  Such an inconspicuous detail error was keenly captured by the Shanghai Stock Exchange. In the "Regulatory Work Letter", the Shanghai Stock Exchange asked the company "the reasons for the differences before and after the disclosure of overseas assets in the annual report".

  In fact, the overall export volume of heparin industry has been declining since 2020. Jianyou Co., Ltd. is also seeking transformation, and has acquired Meitheal Pharmaceuticals, Inc (hereinafter referred to as Meithail), an American pharmaceutical company, to expand the pharmaceutical business in the American market.

  In 2019, Jianyou completed the consolidation of Meitheal. Meitheal is an important overseas asset of Jianyou, and it is also one of the sources of information disclosure errors in the above-mentioned annual report.

  However, from 2019 to 2023, Meitheal lost more and earned less, with a cumulative net loss of about 100 million yuan. During the period, Meitheal also recalled the products under its name due to the wrong labeling of drug names. Recently, the public information of FDA (US Food and Drug Administration) shows that the status of several drug approvals under Meitheal’s name is "discontinued".

  Looking back now, it is quite unreasonable for Jianyou to acquire Meitheal in some places. Including Jianyou shares had provided loans to Meitheal before its acquisition, Meitheal’s net assets were negative when it was acquired, and Meitheal’s equity was actually "exported to domestic market".

  Image source: The reporter made drawings based on public information such as the announcement of Jianyou shares, () announcement, Sino Medical Announcement, Yuandong Biological Announcement and China Foundation Association.

  Before Jianyou shares increased the capital of Meitheal, the original shareholder of Meitheal was a company registered in Cayman Islands. Who was the controller behind this company? Jianyou shares were not disclosed, but only expressed as "no relationship" with Jianyou shares.

  According to the investigation by the reporter of national business daily, one of the original controllers of Meitheal emerged, that is, Zhao Jin, the former supervisor of Jianyou.

  Meitheal was supported by Jianyou’s share loan.

  In August 2019, Jianyou Co., Ltd. issued a foreign investment announcement, and the company increased its capital by about 95 million US dollars to obtain 83.33% equity of Meitheal83.33%

  Jianyou Co., Ltd. said that investing in its own localized R&D, sales, quality and registration team is crucial for the company to vigorously develop the high value-added generic drug market in the United States.

  According to the announcement, Meitheal was established in December 2016. It is a professional pharmaceutical company headquartered in Chicago, Illinois, USA, focusing on developing, manufacturing, purchasing and selling injectable drugs, which are mainly sold throughout North America. Meitheal mainly focuses on generic injections, providing customers with lower-cost brand-name drug substitutes when the patents have expired, been declared invalid or are determined not to infringe others’ patents. Meitheal has a wide range of products covering anti-infection, tumor lysis and intensive care indications, and has various presentation forms such as single-dose and multi-dose vials, ready-to-use prefilled syringes and premixed bags.

  Image source: screenshot of Jianyou shares announcement

  According to the disclosure of Jianyou, the original shareholders of Meitheal were LYFE Charles Limited (hereinafter referred to as LYFE) and Thomas Shea, holding 99.96% and 0.04% respectively. According to the announcement, LYFE is registered in Cayman Islands with a registered capital of 50,000 US dollars. And Mr. Thomas Shea is the CEO of Meitheal.

  Image source: screenshot of Jianyou shares announcement

  It is worth noting that the owner’s equity of Meitheal was even negative at that time, which was-10.17 million US dollars by the end of June 2019.

  It is also worth noting that before the above capital increase, Jianyou shares had provided loans to Meitheal. Jianyou shares said: "Before this transaction, the target company was solely funded by LYFE, and the company provided it with a loan."

  Image source: screenshot of Jianyou shares announcement

  LYFE contributed $11.5 million to Meitheal in January 2017. Subsequently, LYFE did not invest any more money. Instead, Hong Kong Jianyou Industrial Co., Ltd. (hereinafter referred to as Hong Kong Jianyou), a subsidiary of Jianyou Co., Ltd., provided Meitheal with a loan of about $23 million.

  Jianyou shares disclosed that LYFE and Thomas Shea are not related to the company in terms of property rights, business, assets, creditor’s rights and debts, and personnel.

  Who is the actual controller of LYFE registered in Cayman Islands? Meitheal was established with a capital of more than 10 million dollars, but it was able to obtain the loan of Jianyou shares in difficult times, and then it was able to obtain the investment of Jianyou shares.

  Jianyou shares only disclosed in its announcement that 100% shareholders of LYFE are Lyfe Capital Fund II, L.P., but did not disclose the shareholders and actual controllers behind Lyfe Capital Fund II, L.P.. With the deepening of the reporter’s investigation, the real controller behind LYFE Capital Fund II, L.P surfaced.

  It has accumulated a loss of 100 million yuan in five years, and there have been drug recalls in the United States.

  From 2019 to 2021, Meitheal realized operating income of about 800 million yuan, 690 million yuan and 1.04 billion yuan respectively, and realized net profit of about 7,696,600 yuan,-56.32 million yuan and 27.371 million yuan respectively.

  Just after Meitheal realized a profit of more than 27 million yuan, in July 2022, Jianyou announced that after Hong Kong Jianyou bought 16.66% equity of Meit Heal held by LYFE with $21 million in cash, Hong Kong Jianyou would hold 99.99% equity of Meitheal16.66%

  Image source: The reporter made drawings according to the announcement of Jianyou shares.

  "After the company acquired Meitheal, a local American company, in October 2019, combined with Meitheal’s advantages in GPO and channel, the company’s business continued to expand in the US market and its market share continued to expand. In 2020 and 2021, Meitheal’s operating income increased substantially, and it was profitable in 2021. " Jianyou shares said.

  Obviously, the reason for this operation is that Jianyou shares are very optimistic about the development of Meitheal. However, after Jianyou shares were consolidated with Meitheal, from the financial performance, Meitheal’s profit was true.

  Just after the completion of the above minority acquisition, Meitheal lost nearly 80 million yuan in 2022. Throughout 2019 to 2023, Meitheal was in a state of losing more and earning less, with a cumulative loss of about 100 million yuan in five years.

  According to the 2022 annual report of Jianyou Co., Ltd., Meitheal holds a total of 40 FDA-approved drug approvals.

  According to the reporter’s inquiry, the latest FDA approval shows that five of the above 40 drug approvals are in discontinued market status, namely ANDA211003 calcium levofolinate injection, ANDA077096 carboplatin injection, ANDA206190 cytarabine injection, ANDA201166 Topotecan hydrochloride injection and ANDA206189 cytarabine injection.

  Image source: FDA official website screenshot

  It is worth noting that Meitheal once had a drug recall in the United States. According to the FDA official website, in January, 2021, Meitheal recalled the drug due to an error in the drug label.

  Image source: FDA official website screenshot

  According to official website information of FDA, Meitheal announced that it voluntarily recalled a batch of Cisatracurium Besylate (atracurium benzenesulfonate) injection. The decision to recall the product was made after receiving a product complaint. The complaint showed that a part of the carton with batch number C11507A was labeled with Cisatracurium Besylate injection, with 10 bottles in each box, of which 10 bottles were wrongly labeled as Phenylephrine Hydrochloride (phenylephrine hydrochloride) injection.

  In this regard, the reporter of national business daily sent an Interview Letter to Jianyou Co., Ltd. on the reasons for the suspension of the above-mentioned drugs and the reasons for the drug recall. Jianyou shares replied to the interview that the company formulated different product strategies according to different markets. Product strategies will be different in different markets in different periods. The product update iteration in the pharmaceutical market is very normal, and there are countless such cases in major pharmaceutical companies in the United States, such as PFIZER and SANDOZ. At the same time, Jianyou shares also provided reporters with screenshots of recent discontinued products of PFIZER and SANDOZ.

  Regarding the drug recall, Jianyou Co., Ltd. said: "The company did have this recall. The specific recall situation and reasons can be found on the official website of the US FDA. The incident is not important and did not meet the disclosure standards."

  Meitheal’s shareholders are actually "exporting to domestic sales"

  "Through the acquisition of Meitheal, the company’s R&D products can carry out marketing and order acquisition in advance in the R&D stage, so that the company’s products can complete the preparatory work for listing and sales more quickly, and expand the profit period and space." Jianyou Co., Ltd. once described the reason for investing in Meitheal when it first increased its capital.

  However, as a matter of fact, Meitheal didn’t bring profit expansion to Jianyou, on the contrary, it also caused a big loss.

  Image source: The reporter made drawings according to the announcement of Jianyou shares.

  As for LYFE, the original shareholder of Meitheal, Jianyou shares only disclosed that its shareholder was Lyfe Capital Fund II, and L.P. was gone.

  It is worth noting that the main body of LYFE Capital’s WeChat WeChat official account is Zhouling Private Equity Fund Management (Shanghai) Co., Ltd. (hereinafter referred to as Zhouling Private Equity). Meitheal is listed as one of the projects invested by Zhouling Private Equity official website.

  Image source: Zhouling Private Equity official website screenshot

  Zhouling Private Equity was established in April 2015, and its legal representative is Zhao Jin. According to the relevant resume published by China Fund Industry Association, Zhao Jin once worked for Morit Group, Weiwu Capital and other companies.

  Image source: screenshot of China Fund Industry Association

  The reporter noticed that Sino Medical (SH688108, share price of 8.46 yuan, market value of 3.5 billion yuan) also involved in the IPO process related to the upper-level equity structure of LYFE Capital Fund II, L.P, which provided an answer to solve this problem.

  At that time, the exchange asked whether the equity of the transferee issuer, such as Sino Medical, LYFE Capital set up by Jifeng Capital, a domestic investment institution, was in compliance with foreign exchange management laws and regulations, and whether there was a potential risk that the issuer would bear civil and criminal liability or be punished by administrative punishment.

  In September 2019, when Sano Medical responded to the inquiry, it said that according to the information provided by LYFE Capital, as of the date of issuing the reply report, the limited partners of LYFE Capital Fund II, L.P were mainly overseas professional parent funds, management parent funds, family funds, insurance funds and equity investment funds.

  Image source: screenshot of Sino Medical Announcement

  The upper level of LYFE Capital Fund II, L.P includes limited partners and general partners, and who are these limited partners behind the scenes is not disclosed by Sino Medical.

  However, for the general partner, Sino Medical has given a clear shareholding path. The general partner of LYFE Capital Fund II, L.P is Lyfe Capital Management Limited (BVI), and this company is 100% controlled by Shanghai Jirong Investment Consulting Partnership (Limited Partnership), and the general partner of Shanghai Jirong is Jiaxing Jifeng Equity Investment Management Co., Ltd. (hereinafter referred to as Jiaxing Jifeng). Natural persons Zhao Jin and Yu Zhengkun jointly controlled Jirong in Shanghai and Jifeng in Jiaxing.

  In other words, in that year, China enterprises actually controlled Meitheal, and the actual controllers behind them were Zhao Jin and Yu Zhengkun. Jianyou’s investment in Meitheal is similar to the operation method of "exporting to domestic sales".

  One of the original actual controllers of Meitheal is a former supervisor of Jianyou.

  From the common sense, the financial strength, medical industry experience and management ability of Jianyou shares are better than that of a private investment fund. Then, why did Jianyou lend money to Meitheal, and then spent a lot of money to buy it, instead of directly operating and setting up an American subsidiary?

  According to the reporter’s investigation, many evidences show that Zhao Jin, one of the actual controllers of LYFE Capital Fund II, L.P, used to be the supervisor of Jianyou.

  According to the prospectus of Jianyou Co., Ltd. (the declaration draft was submitted on March 15th, 2016), there was a supervisor named Zhao Jin within the reporting period. According to the introduction of Jianyou Co., Ltd., its former supervisor Zhao Jin was nominated by Weiwu (Chengdu) Biotechnology Venture Capital Co., Ltd. [hereinafter referred to as Weiwu (Chengdu)].

  In August 2015, Jianyou Co., Ltd. held an extraordinary general meeting of shareholders, and Zhao Jin no longer served as the supervisor of Jianyou Co., Ltd..

  According to the prospectus of Jianyou, its former supervisor, Zhao Jin, is also a director of Hanerxi (Beijing) Technology Co., Ltd. and Shanghai Jingfeng Pharmaceutical Co., Ltd.. In addition to this information, Jianyou shares did not introduce the former supervisor in detail.

  Image source: screenshot of Jianyou shares prospectus

  According to Jianyou, JEF, Generic and Weiwei (Chengdu) are funds managed by VIVO Ventures, holding 3.0007%, 2.2506% and 0.2813% of the total share capital of Jianyou respectively. JEF, Generic and Weiwu (Chengdu) managed by VIVO Ventures hold 5.5326% of the shares of Jianyou.

  Image source: screenshot of Jianyou shares prospectus

  It is worth noting that the Chinese translation of VIVO Ventures is Weiwu Venture Capital.

  At that time, Shanghai Jingfeng Pharmaceutical Co., Ltd., the enterprise of which Zhao Jin was a director, is now called Shanghai Jingfeng Pharmaceutical Co., Ltd., which is a subsidiary of listed company *ST Jingfeng (SZ000908, share price 1.18 yuan, market value 1.038 billion yuan). According to the announcement of *ST Jingfeng, Zhao Jin used to be a consultant of Morit, and now he is the managing partner of Vivo Ventures, and he is the supervisor of Jianyou Co., Ltd., and the chairman of Hanerxi (Beijing) Technology Co., Ltd.

  According to the resume of Zhouling Private Equity Zhao Jin disclosed by the Fund Industry Association, Zhao Jin also worked as a senior consultant in Molit Group and a managing partner in Weiwu Capital. Then, is it a coincidence that Zhao Jin disclosed by *ST Jingfeng worked in Molit and Vivo Ventures and that Zhao Jin disclosed by China Fund Industry Association worked in Molit Group and Weiwu Capital?

  Image source: *ST Jingfeng announcement screenshot

  On the other hand, Zhao Jin disclosed by *ST Jingfeng was the chairman of Hanerchi (Beijing) Technology Co., Ltd., which provided important clues.

  In April 2019, Yuandong Bio (SH688513, share price of 30.5 yuan, market value of 5.384 billion yuan) was disclosed in its prospectus, and its director Zhao Jin also served as the chairman of Hanerxi (Beijing) Technology Co., Ltd. At the same time, Yuandong Bio provided a detailed resume of Zhao Jin, and Zhao Jin has worked in many companies. Among them, in Jiaxing Jifeng, Zhao Jin holds 50% of the shares and serves as executive director and manager; In Shanghai Jirong, Zhao Jin holds 40% of the property and acts as the appointed representative of the executive partner.

  Image source: Screenshot of Yuandong Biological Announcement

  At this point, the answer is clear. Zhao Jin, the former supervisor of Jianyou Co., Ltd., is one of the original actual controllers of Meitheal.

  As to who is the ultimate actual controller of LYFE, Jianyou Company stated in an interview letter to the reporter of national business daily that according to the announcement of Jianyou Company’s Foreign Investment in 2019 (announcementNo.: 2019-055), the shareholder of LYFE is LYFE Capital Fund II, L.P, which holds 100% equity of Lyfe. According to the public information on the Internet, LYFE Capital Fund II, L.P belongs to LYFE CAPITAL, and its founder and managing partner is Zhao Jin. Therefore, the ultimate actual controller of LYFE is Zhao Jin.

  Regarding the question "Is Zhao Jin, your supervisor in Si Qian, one of the former actual controllers of Meitheal?" asked in the Interview Letter. If so, did any other directors of your company participate in Meitheal’s previous shareholding? If not, can your company provide corresponding reasons? " Jianyou shares replied: "Zhao Jin, the former supervisor of the company, was appointed by VIVO, an early shareholder of the company (at that time, Zhao Jin was a global partner of VIVO), and Zhao Jin became a director of Meitheal as a global partner of LYFE. There are no other directors in the company who participate in Meitheal’s shareholding. "

  In addition, the reporter also issued an "Interview Letter" to Zhouling Private Equity on related issues, but as of press time, no response was received from the other party.

  To sort out the timeline, the operations of Jianyou and Zhao Jin about Meitheal are as follows:

  In April 2015, Zhouling Private Equity was established, with Zhao Jin as the legal representative.

  In August 2015, Zhao Jin ceased to be the supervisor of Jianyou.

  In December 2016, Meitheal was established, and Zhao Jin, as one of the actual controllers, was controlled by Lyfe (registered capital of US$ 50,000) which was finally established in Cayman Islands through a number of companies.

  In January 2017, LYFE contributed $11.5 million to Meitheal.

  From 2018 to the first half of 2019, Jianyou shares borrowed $23 million from Meitheal.

  In October 2019, Jianyou Co., Ltd. increased its capital by about US$ 100 million to obtain 83.33% equity.

  In 2021, Meitheal achieved a profit of 27.371 million yuan.

  In the second half of 2022, Jianyou shares purchased 16.66% equity of Meit Heal held by LYFE in cash of 21 million US dollars.

  In 2022, Meitheal lost nearly 80 million yuan.

  In 2023, Meitheal lost RMB 2,538,200.

Take anti-inflammatory drug infusion as soon as you have a cold and fever? Bacterial drug resistance is more harmful

  In daily life, many people ask doctors for anti-inflammatory drugs and infusion when they have a cold and fever, thinking that this is "getting better quickly". As everyone knows, this is a typical abuse of antibiotics, and its biggest harm is to cause bacterial resistance. Zhong Nanshan, a famous respiratory expert and academician of China Academy of Engineering, said recently that there are various causes of inflammation. Antibiotics are aimed at infections caused by bacteria or fungi, and should not be used at will. In particular, the use of high-level antibiotics should be strictly controlled to curb bacterial drug resistance.

  Antibiotic abuse is a public health problem facing the whole world.

  Antibiotics are the most powerful weapon in the long and arduous struggle between human beings and bacteria, but the abuse of antibiotics has always been a public health problem facing the whole world. Zhong Nanshan said that the most serious harm caused by the abuse of antibiotics is that bacteria develop drug resistance. If some bacteria producing drug-resistant genes are not killed by antibiotics, they will continue to spread drug-resistant genes. Over time, more and more bacteria will carry drug-resistant genes, resulting in the failure of antibiotics, which brings great difficulties to treatment and increases the cost of treatment.

  It is understood that the abuse of antibiotics includes improper use, inaccurate dosage, improper frequency of use and course of treatment, all of which will lead to bacterial resistance, and eventually lead to "no medicine available". The emergence of "super bacteria" is the serious consequence of bacterial resistance.

  Zhong Nanshan, for example, said that fluoroquinolones are widely used in China, and the resistance to these antibiotics has reached 60%, which is rare in the world. In the past, penicillin was very effective for skin infection and visceral infection caused by Staphylococcus aureus, but MRSA appeared later, which has become one of the important pathogens of nosocomial infection. After carbapenem was introduced into China, it gradually became one of the main antibacterial drugs for treating serious bacterial infections.

  According to a survey data, in some places, the proportion of antibiotics used for colds has reached 60%— 70%, and viral colds don’t need antibiotics at all. "Antibiotics are not equal to anti-inflammatory drugs." Zhong Nanshan has repeatedly stressed.

  In the past, people solved the problem of bacterial resistance by developing new antibiotics and constantly introduced advanced antibiotics, but the speed of developing new antibiotics was far behind the pace of bacterial resistance. Therefore, strengthening antibiotic management, strictly controlling abuse and rational use are the key and effective means.

  In addition, the problem of antibiotic abuse not only occurs in medical treatment, but also in animal husbandry and aquaculture, which requires the efforts of all sectors of society to jointly curb the problem of antibiotic abuse.

  Find out the difference between antibiotics and anti-inflammatory drugs

  Many people think that antibiotics are anti-inflammatory drugs, but strictly speaking, antibiotics are not anti-inflammatory drugs, they are two different concepts. Wei Bi, School of Pharmacy, Shandong University, said that "inflammation" is the body’s defensive response to external stimuli. Viruses, fungi, bacteria, dust from the air, burns, etc. may all cause inflammation, and its clinical manifestations are redness, fever and pain at the infected site.

  Anti-inflammatory drugs are drugs that can eliminate inflammation. They are divided into two categories, one is non-steroidal anti-inflammatory drugs, and the other is glucocorticoid. Antibiotics are drugs that kill microorganisms and belong to "bactericidal drugs". Inflammation caused by bacterial infection can be treated with antibiotics; Not inflammation caused by bacterial infection, antibiotics can’t play any role.

  At present, antibiotics are often used by people, but if they are used in large quantities or abused, people will develop drug resistance, resulting in many diseases that are difficult to treat. Therefore, under normal circumstances, antibiotics should be used under the guidance of a doctor. Don’t blindly choose by yourself. At the same time, pay attention to its dosage and frequency of use, and don’t stop taking drugs without authorization. The best way to treat inflammation is to choose appropriate drugs, find the cause and prescribe the right medicine, and follow the doctor’s advice.

  People often use antibiotics and anti-inflammatory drugs to treat various inflammations. In real life, there are many inflammations with the word "inflammation", but can these diseases with the word "inflammation" really be treated with antibiotics and anti-inflammatory drugs? That was not the case. Such as "osteoarthritis". Many people think that its symptoms are joint inflammation and need to be treated with antibiotics or anti-inflammatory drugs. However, osteoarthritis is a chronic bone and joint disease that leads to joint degeneration or bone hyperplasia due to articular cartilage degeneration and damage. Its pathogenesis is not caused by viruses, fungi and bacteria, but by obesity, old age, heredity and other factors. Generally, physical methods are needed to improve the treatment.

  Therefore, if there are some symptoms that you can’t judge yourself, don’t rush to treat with antibiotics or anti-inflammatory drugs. You should seek medical advice in time to find out whether it is caused by bacterial, fungal or viral infection, and then do the treatment. You should start from the pathogen and prescribe the right medicine.

  Rational use is the key to the management of antibiotics.

  The report issued by the World Health Organization pointed out that the drug resistance of antibacterial drugs has posed a serious threat to human health. At present, it is necessary to prevent the abuse of antibacterial drugs, reduce the occurrence of bacterial resistance and help the public to establish the concept of scientific and rational drug use. At the G20 Summit held in Hangzhou in 2016, the issue of dealing with antibiotic resistance was written into the summit communiqué and became a strategic issue at the national level. Zhong Nanshan said that in China, the problem of antibiotic abuse and bacterial resistance is prominent. National Health Commission has successively issued a series of related policies to define and regulate the diseases and high-level antibiotics that should not be used. For example, advanced antibiotics can only be used with the consent of high-level doctors; Consciously control the rate of using antibiotics in outpatient and ward.

  In recent years, the intensity and level of antibiotic management in China have been continuously strengthened. In 2016, National Health Commission and 14 ministries and commissions jointly issued the National Action Plan to Contain Bacterial Resistance (2016-2020). In 2017, the former National Health and Family Planning Commission set up an expert committee on the clinical application of antibacterial drugs and the evaluation of bacterial resistance at the national level, with Zhong Nanshan, an academician of China Academy of Engineering, and Zhao Yupei, an academician of China Academy of Sciences as the chairmen, and organized experts from all over the country to provide technical guidance on the rational use of antibiotics and bacterial resistance. First of all, the Committee has promoted a series of educational activities, such as how to correctly treat the drug resistance of carbapenem; Secondly, the relevant technical provisions were formulated, and based on the research on the clinical application of antibacterial drugs, the situation of bacterial resistance, the spectrum of infectious diseases and the economic burden of bacterial resistance in China, specific technical specifications and technical evaluation were provided.

  Experts believe that in the long run, it is necessary to promote the rational use of antibiotics through professional behavior, including improving the ability of doctors to use antibiotics rationally, making people understand the dangers of using antibiotics at will, and at the same time preventing bacterial infections and controlling nosocomial infections. Only when these aspects are improved, it is possible to use antibiotics rationally and curb bacterial resistance.

  "In the previous stage, the management of antibiotics in China was mainly based on administrative means, which controlled the overuse of antibiotics and gradually moved closer to professional management in the future. The combination of administrative management and professional management can make the rational use of antibiotics go faster. " Zhong Nanshan said. He stressed that the key to the management of antibiotics lies in rational use, rather than simply reducing the dosage. If an antibiotic is not used in time, it will also delay treatment.

  How to distinguish antibiotics from anti-inflammatory drugs?

  The best way is to read the instructions. If you don’t understand them, there is a simpler way: most of the drugs that contain the words "mycin", "bacteriocin" and "ofloxacin" in their names are antibiotics (a few are chemotherapy drugs), such as amoxicillin, ampicillin, benzylpenicillin, carbenicillin, etc., which belong to the classic "penicillin" antibiotics.

  There are generally two types of anti-inflammatory drugs: one is often said to have "loose" hormones, such as cortisone, hydrocortisone, dexamethasone and so on; The other is anti-inflammatory painkillers, such as ibuprofen and aspirin.

  Experts remind that what medicine is used for bacterial infection is not expensive, new or imported, and patients must strictly follow the doctor’s advice.

State Administration of Market Supervision: The unqualified detection rate of online shopping for children’s products is 28.9%.

  CCTV News:The sampling results of online shopping for children’s products in 2018 released by the State Administration of Market Supervision today (23rd) showed that among the 462 groups of goods actually delivered, 61 groups of goods had no factory name and address, and 116 groups of unqualified goods were detected, with an overall unqualified product detection rate of 28.9%.

  13 home appliance platforms, including JD.COM, Amazon, Dangdang, Honeybud.com, Vipshop, Gome Online, No.1 Store, Baby Friendly Room, Mother and Baby Home, Tmall Mall, Taobao.com, Beibei.com and Mushroom Street, were selected for the quality sampling of online trading children’s products, involving seven categories of children’s products: children’s shoes, children’s toys, children’s clothing, baby diapers, roller skates, toy scooters and baby straps (bags). Among them:

  62 groups of children’s shoes were sampled, and 55 groups actually arrived, including 7 groups without factory name and address. After testing, 16 groups were unqualified, and the detection rate of unqualified products was 33.3%.

  60 groups of children’s toys were sampled, and 53 groups actually arrived, including 3 groups without factory name and address. After testing, 2 groups were unqualified, and the detection rate of unqualified products was 4%.

  39 groups of children’s diapers were sampled, and 39 groups actually arrived. After testing, all the samples were qualified;

  40 groups of roller skates were sampled, and 40 groups actually arrived. After testing, 19 groups were unqualified, and the detection rate of unqualified goods was 47.5%.

  40 groups of toy scooters were sampled, and 40 groups actually arrived, including 5 groups without factory name and address. After testing, 16 groups were unqualified, and the detection rate of unqualified products was 45.7%.

  25 groups of baby suspenders (bags) were randomly selected, and 25 groups actually arrived. After testing, 8 groups were unqualified, and the detection rate of unqualified goods was 32%.

  210 groups of children’s clothing were sampled, and 210 groups actually arrived, including 46 groups without factory name and address. After inspection, 55 groups were unqualified, and the detection rate of unqualified products was 33.5%.

  Zhou Shiping, director of the Consumer Protection Bureau of the State Administration of Market Supervision, said that the sampling inspection of commodity quality in the circulation field is a targeted sampling inspection. The seven commodity varieties selected for the sampling inspection of online trading children’s products are the targeted targets determined by the market supervision departments of the four provinces (cities) entrusted with the task after analyzing the data of local consumer complaints and reports, and then determined by the General Administration after overall planning and balance. The main purpose of sampling inspection of commodity quality in circulation field is to prevent the risk of endangering personal and property safety. Detection indicators mainly focus on key indicators related to personal and property safety, rather than "full physical examination" of commodities. The published qualified commodities refer to the commodities whose key indicators are qualified.

  According to the latest analysis data of the State Administration of Market Supervision, in 2017, there were more than 10,000 complaints and reports about children’s products nationwide, a sharp increase of 36.3% year-on-year, making it one of the fastest growing commodity varieties.

  It is understood that in 2018, the results of the special sampling inspection on the quality of online trading children’s products and the list of unqualified products have been announced on the website of the State Administration of Markets. (CCTV reporter Wang Wei)

Sichuan car owners, the authoritative answer to the hot issues of ETC that you want to know is here!

People’s Daily Online, Chengdu, September 16 According to the official news of the Expressway Administration Bureau of the Sichuan Provincial Department of Transportation, at present, the total mileage of expressways in Sichuan Province has exceeded 75 kilometers, ranking second in the country; The number of ETC users in the province is nearly 10,000, ranking eighth in the country; The comprehensive utilization rate of ETC in the province is 75.9%, and the average daily traffic volume is about 1.58 million vehicles/time, ranking first in the country.

On September 15th, Jian Huang, Secretary of Discipline Inspection Commission and Deputy Director of Expressway Administration Bureau of Sichuan Provincial Department of Transportation, visited Sichuan Jiaoguang Live Studio to interpret expressway policies and regulations in the form of live broadcast, answer hot issues of ETC and respond to the concerns of the majority of car owners.

1. Is the ETC charging system stable at present?

Huang Jian: Stable. Please rest assured that the majority of car owners and friends can use it. The toll collected by ETC must always be less than or equal to the actual receivable amount. The last program (click to view it in the past) has been answered. If you still have unclear friends, you can log on to the official website of the Sichuan Provincial Department of Transportation or follow the WeChat WeChat official account of the Sichuan Provincial Department of Transportation to find out.

2. What should I do if the vehicle can’t leave the station normally (there is no vehicle information at the exit) because the entrance speed of the toll station is too fast?

Huang Jian: When the owner encounters this situation, he needs to seek help from the toll booth staff in time. Under the condition of ensuring safety, he will change the vehicle to the manual passage, pull out the ETC card and hand it over to the toll collector, who will check the specific information by technical means and charge the toll according to the actual traffic path of the vehicle. At this time, he can use ETC to deduct the toll and enjoy the ETC preferential policies normally. At the same time, we are also urging the expressway operating companies to further strengthen the business training for toll collectors and provide better services for car owners and friends.

3. Recently, we have noticed that some car owners have complained that they don’t know what to do when entering and leaving the high-speed ETC. Can you give us a detailed answer?

Huang Jian: When entering and leaving the expressway, if the vehicle in front rubs the ETC first, the owner needs to seek help from the toll booth staff in time. After the staff verifies the on-site situation in the toll collection system, the passage will be charged according to the normal situation. If the owner rubs the rear vehicle ETC first when driving into the high speed, the treatment will be the same as mentioned above; If the owner rubs the rear vehicle ETC first when driving out of the expressway, the toll booth staff will conduct an audit through technical means to recover the toll payable by the vehicle.

Therefore, once again remind the majority of car owners and friends to slow down when entering and leaving the expressway, and pay in an orderly manner. Each toll station is equipped with a high-definition smart camera, which can accurately identify and record the license plate number and passing situation of each ETC vehicle. If the vehicle does not have an expressway pass card or driving record due to illegal behavior, it will be treated as no card when driving out of the expressway, and it will be blacklisted and unable to pass the national expressway normally.

4. Why did some truck owners who handled ETC last year report that they could not enjoy ETC concessions normally?

Huang Jian: The single card user of truck ETC is a service mode to realize non-cash payment for trucks under the condition of charging by weight. It can only be used for manual charging. Since it cannot realize fast charging without stopping, it will no longer enjoy the preferential policies of ETC from January 1, 2002. At the same time, before the end of last year, about five ordinary ETC cards were issued to tractors in our province. Therefore, this kind of tractors will not be able to complete the reserved passage due to the lack of key information of vehicles and the mismatch between ETC cards and OBU equipment information.

In this reform of canceling the provincial toll station of expressway, in order to realize the fast passage of trucks without stopping and promote the speed-up and efficiency-improvement of the logistics industry, it is required that the charging method for trucks should be adjusted from the charging by weight to the charging by truck (axle) from January 1, 22. Therefore, the owners of these trucks are requested to go to the issuing bank in time to install ETC on-board devices and improve the actual information of vehicles for free, so as to ensure that they can continue to enjoy various ETC preferential policies (including the basic preferential policy of not less than 5% of vehicle tolls).

5. Does the truck ETC need to be weighed without stopping when entering the expressway?

Huang Jian: Yes. Since December 16, 2019, the national expressway has fully implemented the non-stop weighing inspection at the entrance. When entering the expressway, truck owners need to take the initiative to enter the weighing platform to weigh according to the lane indicator. The weighing inspection data will be interconnected with the expressway toll card issuing system. If it is confirmed to be a legal vehicle, the toll system will automatically lift the pole and release it; If it is confirmed to be an illegal overloaded vehicle, the toll collection system will prohibit lifting the pole and refuse it to enter the expressway, and the owner must leave according to the route guided and arranged by the staff.

6. How do large transport vehicles pass through the expressway?

Huang Jian: By logging in to the Trans-provincial Parallel Permit System for Bulk Transportation, an application is submitted. After the application is approved, the system will automatically forward the information of the permission list to the applied toll station on the expressway entrance. After the vehicle is weighed and tested, the entrance toll station manually checks the vehicle outline size, and the toll collection system automatically checks the conformity of the vehicle license of large transport vehicles. If the information is consistent, it will be allowed to be released, and a sign of "large-piece transportation" will be marked in the ETC vehicle-mounted device, and the ETC gantry will be charged and deducted according to the over-limit transportation rate along the way.

7. What should I do if the vehicle with ETC installed cannot drive into the high-speed normally?

Huang Jian: If the owner friend encounters this situation, he needs to change the vehicle to the manual passage, and pay the fee normally according to the vehicle without ETC card when leaving the station. After the passage, you can call the ETC customer service number (28-12122) to reflect the specific situation. When it is verified that the ETC of the vehicle cannot be used for technical reasons, it will be charged according to the ETC vehicle preferential policies. At the same time, the same applies to truck owners in similar situations.

8. What should I do if I prompt the blacklist when I pass the ETC lane?

Huang Jian: Generally, when the ETC lane is prompted to be blacklisted, only the manual passage is temporarily selected, and the ETC lane will be used after the next blacklist is lifted. There are two ways to cancel the blacklist: if the blacklist is added by the bank, it is generally because the balance of the bank card is insufficient or overdue, and you need to contact the bank to handle it and apply for cancellation; If it is joined by ETC customer service center, it is generally because the audit found that the vehicle type does not match the actual situation, and it is suspected of evading tolls. It is necessary to go to the bank to change the vehicle information to the actual vehicle type and cancel it. In addition, the lifting of the blacklist involves data updating and synchronization, which requires a certain processing time. If it still cannot be used normally after 48 hours, please go to the bank outlet or call (28)12122 for consultation.

9. How to prevent vehicles from being pulled into the ETC blacklist?

Huang Jian: First, pay attention to the balance in the bank card and repay it in time; The second is to properly keep ETC cards, OBU devices, bank cards and passwords.

10. If I find that my car has been occupied and registered for ETC, how should I cancel it?

Huang Jian: If it is occupied by an issuer outside the province, please pay attention to the official WeChat WeChat official account of the Ministry of Transport or the WeChat applet of "China ETC Service" and use the "Cancel License Plate Occupancy" business to apply; If it is occupied by an issuer in the province, please pay attention to the "Sichuan Expressway ETC" WeChat WeChat official account, and enter the vehicle license plate number and other related information in the "Online Message" License Plate Occupancy, and apply for canceling the occupation.

11. What information do I need to provide to remove the license plate occupation?

Huang Jian: Personal vehicles need to carry the following documents: owner’s ID card and vehicle driving license (if acting as an agent, power of attorney, agent’s ID card and vehicle authorization); The following documents are required for the company’s vehicles: the ID card of the agent, the vehicle driving license, the power of attorney of the company and the power of attorney of the vehicle. Here, I suggest you consult the ETC issuing bank first before handling it.

Tips

The majority of car owners and friends need to pay special attention in the process of using ETC:

Check ETC device before driving on the road. Focus on checking whether the ETC vehicle is correctly inserted into the ETC card and whether the OBU tag on the vehicle is in a normal state (the ETC card in the OBU can be pulled out first, and then inserted correctly, and if the OBU sounds "beep", it means normal startup). If it is a stored-value card, make sure that the balance on the card is sufficient to avoid traffic obstruction due to insufficient balance.

In and out of the toll station, you must slow down and drive in a special lane. ETC vehicles should take the ETC lane, and non-ETC vehicles should take the artificial lane and get the CPC cartoon line. Don’t change lanes in front of the toll booth or in the station. Try to keep a distance of about 5 meters between ETC vehicles, and don’t be too close to the vehicle, so as to avoid the situation that your vehicle is recognized first and you pay the bill for the vehicle in front. When weighing trucks, it is also necessary to keep the necessary distance between vehicles, so as to avoid congestion caused by lack of space when there are overloaded vehicles in front. Here, we should also remind truck drivers and friends that they must be loaded in a standardized way and transported legally, and overloaded vehicles cannot enter the expressway.

We must standardize civilized driving after entering the expressway. Gantry should drive in the specified lane on the way. Don’t change lanes or speed at will, and don’t pull or insert ETC cards at will on the way, otherwise it will easily lead to abnormal marking and affect the success rate of billing.

Do not destroy the disassembly OBU label. OBU tags are dedicated to special vehicles, and correspond to vehicle information and bank card information one by one. Illegal disassembly will cause the tags to be invalid and unable to pass normally. If it is found that the OBU label of the vehicle has fallen off or loosened, the owner needs to re-install and activate it at the ETC bank service outlet.

Illegal operation of vehicles, malicious arrears and blacklisted vehicles are prohibited from passing through the expressway. At present, the province’s expressways have established a credit joint punishment system. We will severely and accurately crack down on illegally operated vehicles through big data analysis and application, and jointly punish malicious arrears and blacklisted vehicles. The disciplined car owners will not be able to pass the expressway for a certain period of time.

The majority of car owners can directly call the service hotline of ETC business handling bank or the service hotline of Sichuan Expressway at 28-12122 for telephone consultation, or you can pay attention to the WeChat WeChat official account of Sichuan Expressway for self-help inquiry. Please don’t trust the ETC update and certification related information released by other unknown sources or unofficial media, and don’t click on unknown links to ensure the safety of personal information and property and avoid being cheated.

See how the ancient Chinese epidemic prevention.

  The wise ancients knew and dealt with the plague.

  Yin and Shang dynasties We have been able to see the early records of the epidemic and the measures taken to avoid it. Perfect sewers have also been excavated in Yin Ruins, indicating that the city has public health facilities, which is conducive to reducing the occurrence of epidemics.

The picture shows the word "service" (epidemic) in Oracle Bone Inscriptions, which shows that Chinese has known the knowledge about epidemic for a long time. (information photo)

  Zhou royal family Ceremonies to expel the plague were held regularly, and officials responsible for handling the epidemic were also set up. The Classic of Mountains and Seas contains seven kinds of drugs for treating plague, such as smoked grass.

  After Qin and Han dynasties Traditional Chinese medicine tends to be mature, and Huangdi Neijing has a complete idea of disease prevention and treatment. It is suggested that people should strengthen prevention before the onset, or treat it as early as possible in the early stage of the onset and prevent recurrence after treatment.

   Other TCM classics, such as Treatise on Febrile Diseases and Shennong Herbal Classic, provide dialectical prescriptions and drug knowledge for preventing and treating diseases.

  Progressive ideas and means of prevention and control

  Sui dynasty People realize that infectious diseases are caused by "surly qi" and have their own special causes.

  Ming dynasty Wu Youke pointedly pointed out that "Qi is the thing, and the thing is the gas", and the cause may be some invisible substance, which is very close to the hypothesis of microbial etiology.

   In terms of prevention, Hua Tuo proposed to use Tu Su wine, Ge Hong proposed to use Laojun Shenming powder, and later someone proposed to take Huoxiang Zhengqi powder.Tang and song dynasties Aromatherapy was widely used to prevent diseases, and burning Atractylodes lancea was popular in Ming Dynasty to purify the air.

  Mid-Ming dynasty Vaccination against smallpox appeared among the people. Later, some foreign envoys came to study and brought this technology back to Europe. On this basis, the British medical scientist Jenner invented vaccinia vaccination, which laid the foundation for the final elimination of smallpox, a severe infectious disease in the world.

The picture shows the Han Dynasty mural "Hometown Nuo Map" of Wushi Temple in Jiaxiang, Shandong Province, which reflects the concept of expelling poisonous insects and avoiding epidemics in the Han Dynasty.

   as far back asJin dynasty Institutionalized epidemic prevention measures have been formed. The government stipulates that courtiers who have patients and infected more than three people are not allowed to enter the palace for 100 days, although they are not sick.

  Song dynasty Pay attention to the disposal and cremation of the bodies of the infected dead as soon as possible.

  Qing dynasty There is a "pox shelter" in the court to isolate people infected with smallpox, and it is stipulated that relatives can visit after nine days of isolation.

  A benevolent doctor in the epidemic

   Epidemic prevention and treatment are inseparable from doctors. In ancient China, a group of great doctors stood up in the great epidemic and left valuable spiritual wealth and treatment experience for future generations.

   During the Song Dynasty, there were many epidemics, and the government often sent medical officers to local areas to distribute drug relief. Li Tang’s Map of Village Doctors in Song Dynasty vividly depicts the situation of doctors treating patients. (information photo)

  At the end of the Eastern Han Dynasty, the plague raged. Famous doctor Zhang Zhongjing The clan originally had more than 200 people, and two-thirds of them died in 10 years. In his grief, he wrote Treatise on Exogenous Febrile Diseases, which became a model of TCM syndrome differentiation and treatment. He emphasized that doctors should have the spirit of "helping the relatives from the top and saving the poor from the bottom", and carried out the rigorous attitude of "assiduously seeking the ancient teachings and learning from others" in research medicine, which was called by the later Buddha."medical sage".

  Sun Simiao, a famous doctor in Tang Dynasty More than 600 leprosy patients with chronic infectious diseases who were discriminated by society were treated, and doctors were required to "not look ahead and look back, think about good or bad, and protect their lives" when treating patients, which established the medical ethics norms of traditional Chinese medicine, and their medical ethics were deeply admired by later generations."drug king" Known as.

Wu Youke’s Treatise on Epidemic Fever in Ming Dynasty is the first monograph on plague in China. (information photo)

   In 1232, a great epidemic broke out in the capital of song dynasty, killing more than 900 thousand people. At that time, famous doctorsLi Gao The "Puji Disinfection Drink" was created, which was very popular, and people carved the prescription on stone tablets to spread it. His studentsLuo tianyi He also became a famous doctor who was good at saving the epidemic, and treated many officers and men infected with the epidemic in the Yuan Dynasty.

  Many famous prescriptions of traditional Chinese medicine that are still in use today are summarized by famous doctors in actual combat. Such as Wu Youke’s Dayuan Drink, Yinqiao Powder from Ye Tianshi and Wu Jutong, Yu Shiyu’s Qingwen Baidu Drink, Yang Lishan’s Shengjiang Powder and Wang Qingren’s Jiedu Huoxue Decoction.

   In the face of various plagues, groups of benevolent doctors in ancient China did not shrink back, did not avoid difficulties and dangers, and repeatedly studied the treatment in practice, and gained very valuable experience, which saved countless lives and made great contributions to the epidemic prevention and anti-epidemic in ancient society.

Road test and sailing: a new trend of automatic driving of automobile enterprises from the auto show

  [News] With the gradual opening of road test, can autonomous driving be far behind? Not long ago, the country issued the specifications of road test related to intelligent driving, and Shanghai, Fujian, Chongqing, Shenzhen, Changchun, Changsha and other places have also issued relevant road test rules one after another, but only Beijing, Shanghai and Chongqing issued the number plate for road test. Among them, Shanghai was the earliest. On March 1 this year, Shanghai issued a road test number plate to SAIC. Chongqing has the most. On April 18th, Chongqing issued license plates to seven companies: Baidu, Guangzhou Automobile, Geely and Beiqi. Beijing’s latest, during the auto show, Beijing just announced that Weilai won the number plate (Beijing had previously issued a number plate to Baidu). Taking advantage of the east wind, let’s take a look at the progress of these car companies that have obtained number plates in the field of intelligent driving.

Home of the car

Beiqi New Energy: Releasing "Darwin System"

  BAIC New Energy, which just got the number plate, released the vehicle artificial intelligence system "Darwin" at this auto show. British biologist Darwin’s theory of evolution has a basic view: evolution has no direction and no end. Correspondingly, the Darwin system can also realize continuous self-learning and growth. In the future, BAIC New Energy will carry up to 546 chips on a bicycle to handle data requirements, and upgrade the OTA (over-the-air program) of the whole vehicle.

  As the pioneering work of "Darwin System", BAIC new energy EU5 was officially listed at Beijing Auto Show. The vehicle model integrates 10 intelligent driving assistance devices and technologies, including lane departure warning, pedestrian collision warning, vehicle collision warning, automatic emergency braking and other auxiliary driving technologies. With EMD 3.0 intelligent electric drive technology, it can accurately monitor driving safety and correct the path in real time.

Home of the car

  BAIC New Energy mainly cooperates with Baidu, Bosch and Harman in the field of automatic driving to realize the research and development of intelligent driving functions including ADAS intelligent assisted driving system, L3 automatic driving, intelligent cockpit monitoring and parking service. Among them, the intelligent cockpit system with multiple application scenarios will be fully equipped on the models listed in 2018-2020.

  The road to autonomous driving BAIC New Energy will also rely on the strength of BAIC Group. According to the plan, BAIC Group’s vehicles will be Baidu’s open platform, and L3 self-driving vehicles will be mass-produced around 2019, and L4 self-driving vehicles will be mass-produced around 2021. The driverless plan of BAIC New Energy may also be promoted according to this.

Weilai: the only car company that got the number plates of two places.

  Consistent with the new energy qualification review, the choice of intelligent driving license plate is also more inclined to traditional car companies at present. Among the eight car companies that have obtained road test license plates in various provinces and cities, only Weilai Automobile is a new car company, and it is also the only passenger car company that has obtained license plates in Beijing and Shanghai.

  At this auto show, Weilai booth was particularly popular. Apart from the car itself, the on-board artificial intelligence system "NOMI" is also eye-catching. Based on the powerful on-board computing capability and cloud computing platform, it integrates a voice interaction system and an intelligent emotion engine, which can talk with people, automatically adjust the temperature inside the car, automatically purify the air inside the car, and help car owners take selfies.

Home of the car

  As an emerging car company, Weilai has been committed to intelligent driving research and development. In the ES8, the first model of Weilai released at the end of 2017, the automatic assisted driving system NIO was equipped. In the scheme of perception system, there is a three-eye camera, four panoramic cameras, five millimeter-wave radars, 12 ultrasonic sensors and a driving state detection camera. It can achieve more than 20 core capabilities such as adaptive cruise, high-speed automatic assisted driving, congestion automatic driving, automatic road maintenance, parking assistance, automatic parking, active vehicle call and fatigue warning.

  Weilai mainly cooperates with leye, NVIDIA and NXP in the field of intelligent driving. At present, a large number of automatic driving function tests have been completed, including simulation tests and closed road tests. At the same time, Weilai launched the open road test plan in California, Beijing, China and Shanghai. According to the plan, Weilai will release vehicles with L4-level automatic driving capability in 2020.

Saic: zebra intelligent system welcomes version 3.0.

  As a car company that proposed "Internet car" earlier, on the eve of this auto show, the Marvel X, a brand-new pure electric vehicle of SAIC, officially made its debut. It is reported that the car is equipped with AR augmented reality technology, version 3.0 Internet car zebra intelligent system, all-round intelligent welcome system, as well as wireless charging, automatic parking and parking functions.

Home of the car

  SAIC has a long history in the field of intelligent driving. When it was launched in 2015, it already had intelligent driving assistance function. When the speed is 60-120 kilometers per hour, it can realize automatic cruising, automatic car following, lane keeping, lane changing and autonomous overtaking. In the field of new energy, both Roewe ERX5 and Roewe ERX 5 are equipped with zebra Zhixing system, which can realize the above intelligent driving assistance function. Not long before the auto show, SAIC announced that the upgrade of Zebra Zhixing System 2.0 on Roewe ERX5 will be started, and users can enjoy the OTA upgrade service for free. At that time, users will receive download prompts and updates, including maps, voice and HMI. All interfaces will be updated.

  In the field of intelligence, SAIC mainly cooperates with Ali. As early as July 2014, the two sides signed a strategic cooperation agreement and formally established Zebra Zhixing Company, which is committed to providing the overall solution of Internet vehicles for the entire automobile industry. At present, it has been applied to a number of SAIC models. At the same time, SAIC also obtained California’s autopilot test license in 2017 to conduct autopilot road test work in the United States.

Chang ‘an: L2 technology will be launched.

  Since the "Shangri-La" plan was released last year, Changan Automobile has made frequent moves in the fields of electrification and intelligence. At this auto show, Changan presented a new generation of CS75, which is equipped with Changan APA4.0 parking service system, which can realize the functions of active parking search, one-button parking inside the car, remote parking outside the car, etc. In addition, Foreign Minister Anxin CS75 is also equipped with Bosch’s new generation AEB early warning auxiliary braking, LCDA intelligence, LDW lane departure warning and many other intelligent driving assistance functions.

Home of the car

  At the same time, the CS55-IACC version of Changan Automobile will be launched soon, which is equipped with IACC integrated adaptive cruise technology and has reached the L2 level of automatic driving. IACC adopts multi-sensor integration technology, integrates millimeter-wave radar, multi-function camera and navigation map, perceives the driving road environment, and controls the automatic acceleration, deceleration and steering of the vehicle through power, braking and steering, so as to keep the vehicle in the lane or follow the track of the target vehicle in front.

  The driverless test of Changan Automobile started two years ago. As early as 2016, Changan driverless car arrived in Beijing safely from Chongqing in five days and completed the 2000km driverless test; In November 2017, Changan Automobile obtained the California road test driverless car test license.

  In the field of autonomous driving, Changan Automobile currently mainly adopts the form of cooperation with other enterprises, and has signed contracts with many enterprises such as Weilai, Baidu, Intel, Alibaba and Tencent. But at the same time, Changan is also doing independent research and development, which will be gradually applied when the technology is mature.

FAW: At present, no action has been implemented in the field of automatic driving.

  Among many license plate car companies, the specific implementation of FAW’s automatic driving in the passenger car field is the most mysterious. At the auto show, FAW exhibited FAW, and the official pointed out that its main theme is "Yan value+intelligence" and it will be listed in 2018. But so far, no further details about the field of intelligent driving have been released, except that the car is equipped with 4G network and has HMI platform.

Home of the car

  As early as April 2015, FAW Group released a complete intelligent interconnection strategy-"Zhitu". According to the plan, by 2020, FAW will gradually carry L3-class automatic driving on a series of products in terms of intelligence; In terms of informatization, combined with the comprehensive application of 5G, a perfect V2X system is established to improve driving safety and traffic efficiency. By 2025, FAW will realize the serialization of L4 self-driving products in terms of intelligence; In terms of informationization, based on the big data of the Internet of Things, we will integrate social travel resources and establish a high-quality mobile travel service ecosystem.

  In the field of intelligent driving, FAW chose Tencent as its small partner. In April this year, Tencent and FAW formally signed a strategic cooperation framework agreement, and the two sides will build intelligent networked products based on Tencent Car’s "AI in Car" intelligent solution.

Dongfeng: Launching Link3.0 System

  During the Beijing Auto Show, the eπ concept car, a new energy concept, was launched on the Dongfeng booth. It can obtain the optimal path planning, provide remote medical treatment, interact with family members in real time, assist users to pay attention to hot spots along the way in real time, and provide real-time travel with real-time interconnection positioning and automatic greeting technology between cars and people.

Home of the car

  In addition to the vehicle model display, it also brought the WindLink3.0 artificial intelligence vehicle system display, which was jointly built by dongfeng fengshen, Baidu and Botai, and realized the functions of one-button navigation, one-button positioning, peripheral search, interest point search, off-line navigation and so on through voice interaction. In addition, it can remotely control the doors, windows, air conditioners and so on through the mobile App, and monitor the vehicle condition in real time. This system will be carried on passenger cars in dongfeng fengshen which will be launched this year, and will cover all product series in the next three years.

  Dongfeng’s layout in the field of intelligent driving has been started since 2013, and it has been technically equipped on mass-produced vehicles in dongfeng fengshen. It has successively launched A60 intelligent prototype in 2013, AX7 intelligent prototype 1.0 in 2014 and AX7 intelligent driving prototype 2.0 in 2017, and completed the engineering and industrialization of new technologies such as automatic parking and intelligent assisted driving. In the field of driverless driving, Dongfeng plans to mass-produce driverless cars by 2020, but it will be used in special fields and commercial fields first.

Guangzhou Automobile Co., Ltd.: In 2019, L4-class autopilot demonstration operation will be realized.

  Guangzhou Automobile mainly focuses on new energy in the field of intelligent driving. At this auto show, the first new energy concept car developed for the North American market was released. Although Guangzhou Automobile did not describe this model in the field of automatic driving, its window did not choose traditional glass material, but it can be integrated with the door when it is closed, which means that the window is opaque and the car can’t be seen outside, so it is judged that the main control mode designed for the Enverge concept car is automatic driving.

Home of the car

  GAC mainly cooperates with Huawei, Tencent, Ali, Cisco China and Didi Chuxing in the field of autonomous driving, and will cooperate in the fields of cloud computing, car networking, intelligent driving, new energy vehicles, big data applications and travel services. According to GAC’s new energy plan, the future is not only to launch new energy vehicles, but more importantly, smart cars. The company plans to realize the demonstration operation of L4-level highly automatic driving in 2019, and gradually upgrade to L5-level fully automatic driving.

Geely: mainly relying on its own strength for research and development.

  At the Beijing Auto Show in 2018, Geely brought GKUI in-vehicle system, which is a deeply customized in-vehicle system based on Android system, and supports many functions such as car networking, car-machine interconnection, navigation, multimedia, third-party App, etc. The system has been used in Geely’s various models.

Home of the car

  The use of the above functions is still in the state of car networking. Geely has not yet equipped with intelligent driving including related auxiliary functions, but it has technical reserves. At present, the models on sale have relied on ACC adaptive cruise system and completed the initial prototype of automatic driving. Starting this year, Geely’s models will be equipped with car networking technology, and intelligent driving assistance functions such as automatic parking will be carried one after another.

  Different from other experts, Geely’s autonomous driving field, like the Internet of Vehicles, mainly relies on its own strength for software and hardware development. It is reported that there are currently 600 teams for hardware development and 400 teams for software development. According to Geely’s plan, it is predicted that L3 system with high automatic driving ability will be realized in 2020, and L4 system with fully intelligent automatic driving will be realized in 2024.

Full text summary:

  Undoubtedly, intelligent driving must be the future direction. According to the feedback from car companies, more and more vehicles equipped with intelligent driving assistance functions will be launched in the next year or two, mostly with L2 level. At the user level, the biggest experience lies in voice recognition, automatic parking, etc. Most cars with L3/L4 level tend to appear around 2025, while the higher L5 level is still far away from the legal level and car company planning for the time being. But in the long run, multi-screen, driverless, and canceling the steering wheel are the future trends. In addition, from the perspective of cost, according to car companies, with the improvement of automatic driving level in the short term, the cost is still rising, but after reaching an order of magnitude, the cost will decline. (Text/car home Zhang Wei)

Rare! Collective changes in Hong Kong stocks and A shares

  Real estate stocks have suddenly become the object of capital pursuit!

  On May 10th, real estate stocks in the A-share and Hong Kong stock markets changed collectively. Shimao Group, a domestic housing stock in Hong Kong stocks, once rose over 90% in intraday trading, and South China City once rose over 70%. The A-share real estate sector rose by nearly 4%, with nearly 10 daily limit shares such as () and (), and Vanke A once rose by nearly 5%. Some analysts pointed out that the stock price of real estate stocks usually reacts faster than the recovery of fundamentals, so the bottom of real estate stocks has been basically clear.

  On the same day, financial stocks such as insurance and banks also changed at the same time as real estate stocks. On the same day, the banking and insurance sectors in Hong Kong rose by 4%. The high dividend sectors of Hong Kong stocks such as energy and electricity also strengthened collectively. In addition, a number of Hong Kong stock dividend-related ETFs rose more than 5%. Among them, the Hong Kong stock exchange dividend ETF, the Hong Kong stock exchange non-bank ETF, the Hong Kong stock exchange financial ETF, the Hong Kong stock exchange dividend index ETF and the Hong Kong stock exchange central enterprise dividend ETF all hit new highs in intraday trading. In this regard, China, a brokerage firm, took the lead in reporting this morning: "Hong Kong, the sudden spread of great benefits! 》

  So, why is the high dividend sector so strong?

  Real estate stocks soared.

  Today, real estate stocks are highly sought after. Shimao Group, a Hong Kong stock, once rose more than 90% in the afternoon, hitting a maximum of HK$ 1.16, and accumulated nearly 160% in two days. South China City once rose more than 70% in intraday trading, and Zhengrong Real Estate, China Aoyuan, Fantasia Holdings and Kaisa Group followed suit. At the close, Shimao Group rose 60%, South China City rose nearly 45%, China Aoyuan and Fantasia Holdings rose over 20%, and Kaisa Group rose 14.55%.

  In the A-share market, the real estate sector also rose sharply. At the close, the overall increase of the sector was close to 4%, and nearly 10 shares of China Merchants Shekou, (), () and Binjiang Group rose by more than 5%, and Vanke A rose by more than 3.56%.

  Some analysts pointed out that the strength of real estate stocks is related to the news that Hangzhou, the core city of the Yangtze River Delta, and Xi ‘an, the core city of the northwest, both announced the cancellation of housing purchase restrictions. The market expects that the regulation policies of first-tier cities will be optimized to the main urban areas, and the pattern of comprehensive cancellation of purchase restrictions in second-tier cities will accelerate. The recent intensive implementation of policies has helped to repair market expectations, and promoted the activity of market transactions, helping sales to gradually stabilize.

  On May 9, Hangzhou issued the Notice on Optimizing and Adjusting the Regulation Policy of the Real Estate Market, and Xi ‘an issued the Notice on Further Promoting the Stable and Healthy Development of the Real Estate Market. On the same day, two high-energy cities further optimized and adjusted their real estate policies, including a series of measures such as completely canceling the housing purchase restriction. Prior to this, Chengdu also issued a document on April 28th to optimize the real estate policy.

  Huatai Securities pointed out that Chengdu, Hangzhou and Xi ‘an are all cities with good chemical conversion rate since the fourth quarter of 2023, and the optimization of real estate policies in these cities is expected to inject confidence into the market. At present, real estate sales have not completely stabilized and rebounded, and the Politburo meeting has continued due to the city’s policy. It is expected that more first-tier cities and strong second-tier cities will introduce more industry support policies, which is expected to promote market confidence and fundamental repair and provide valuation repair space for the real estate sector.

  At present, the market is highly concerned about the fundamental trend after the introduction of the policy, and CITIC Securities believes that by mid-2024, housing prices in the core areas of core cities are expected to stabilize. In addition, () said that a number of core cities have recently introduced policies to relax the purchase restriction, including Beijing’s optimization of the housing purchase restriction policy after 13 years and the addition of a set of housing purchase indicators outside the Fifth Ring Road; Cancel the purchase restriction in Chengdu and Changsha; Tianjin released the purchase restriction of new houses of 120 square meters or more in the six districts of the city; Shenzhen single non-local household registration and two-child household registration families can purchase one suite in some areas. It is expected that under the new policy tone, the pattern of real estate regulation and control policies in first-tier cities will be optimized to the main city and the purchase restriction will be completely cancelled in second-tier cities.

  After the adjustment of Politburo meeting of the Chinese Communist Party, a new round of policies has arrived, the policies of core first-and second-tier cities have been continuously optimized, and more supportive policies can be expected. We believe that the current industry fundamentals are already in the bottom range, and the subsequent decline space is limited, and the valuation of the real estate sector is at a historically low level. The response of real estate stocks is usually faster than the recovery of fundamentals, so the bottom of real estate stocks has been basically clear.

  Du Haomin and Fang Peng, analysts of Guojin Securities, also believe that after Politburo meeting of the Chinese Communist Party’s adjustment, a new round of policies has arrived, the policies of core first-and second-tier cities have been continuously optimized, and more supportive policies can be expected. At present, the fundamentals of the industry are already in the bottom range, and the space for subsequent decline is limited, and the valuation of the real estate sector is at a historically low level. The response of real estate stocks is usually faster than the recovery of fundamentals, so the bottom of real estate stocks has been basically clear. First push the key layout, deepen the first-tier and core second-tier cities, focus on improving products, and have the ability to continuously acquire land.

  The rise of financial stocks

  Financial stocks are also one of the highlights today.

  In the Hong Kong stock market, as of the close, Hong Kong banks and insurance sectors rose by more than 4%, () by more than 8%, China Construction Bank by nearly 7%, () by more than 6%, China Ping An by 5.77%, Agricultural Bank by more than 5%, () by China CITIC Bank and Bank of Communications by nearly 5%. At the same time, the high dividend sectors of Hong Kong stocks such as energy and electricity also rose sharply, with the energy sector rising by more than 4%, () rising by more than 6% and China Petrochemical Co., Ltd. rising by more than 5%.

  Some analysts pointed out that the rise of high dividend assets in Hong Kong stocks such as finance, energy and electricity was mainly influenced by a rumor last night-it was reported that "the dividend tax on Hong Kong stocks may be reduced." However, as of the press release of China reporter, the above news has not been officially confirmed.

  () The report released this morning pointed out that if the bonus tax relief for Hong Kong stocks is implemented, it is expected to further boost mainland investors’ investment enthusiasm for Hong Kong stocks, especially those related to high dividends, boost sentiment in the short term and help improve the liquidity of the Hong Kong stock market in the long run.

  CICC pointed out that in August last year, a liquidity task force was set up in Hong Kong to pay attention to the follow-up measures to improve liquidity. Looking ahead, if the dividend tax adjustment is implemented, it will become another important measure to potentially improve the liquidity of Hong Kong stocks after the reduction of stamp duty in Hong Kong stocks at the end of last year and the introduction of five measures for cooperation with Hong Kong by the Securities and Futures Commission last month. Next, we will not rule out further measures, which may include reducing transaction costs (reducing transaction commissions) in the short term; Lower the investment threshold and broaden the investment scope in the medium term (appropriately relax the entry threshold of Hong Kong Stock Connect and continuously optimize the listing system); Long-term activation of product innovation (optimization of Hong Kong Growth Enterprise Market mechanism, establishment of professional boards for professional investors, etc.).

  Huatai Securities said that the dividend tax not only directly affects the AH premium of listed companies in the two places, but also indirectly affects the investable value of constituent stocks in the scope of Hong Kong Stock Connect to the south. Taking May 8, 2024 as the time parameter, and the stocks within the scope of Hong Kong Stock Connect with a market value of more than HK$ 10 billion and a static dividend yield of more than 5% as the range pool, the sub-sectors with a southbound shareholding ratio of more than 14.9% and a static dividend yield of more than 7% are screened under the holistic method, and the conclusions are as follows: energy, materials, capital goods, automobiles and auto parts and banks. It can be concerned that the investment value of high dividend varieties in related industries may be improved.

President Suning.cn said that Suning stores will break through 10,000 stores, and it is an empty talk for millions of stores.

"double 11" hasn’t arrived yet, and the smell of smoke among merchants has started.

On October 26th, Suning held the kick-off meeting of "double 11 National Carnival" in Nanjing. Hou Enlong, president of Suning.cn, said in his speech that the number of stores in Suning will exceed 10,000 in double 11 this year.

Hou Enlong said that the energy of these 10,000 stores far exceeds that of 1 million ordinary stores, and each store in Suning includes various functions such as goods, services and experiences to achieve refined operation.

"We have actually opened 10,000 Internet stores, and now many people in the industry can do 600,000 or 1 million with a wave of their hands. I think it is more on paper." Hou Enlong said, "Like the pig on the tuyere, it will fall and die sooner or later. This simple use of data to make traffic go offline is untenable. "

Hou Enlong’s statement was interpreted as challenging his opponent JD.COM. Liu Qiangdong, the founder of JD.COM, announced in 2017 that more than 1 million JD.COM convenience stores will be opened nationwide in the next five years, with the opening rate of 1,000 stores every week.

It’s not the first time that Hou Enlong, president of Suning.cn, "choked" Liu Qiangdong.

At an event in July, 2018, the host asked questions about JD.COM’s advantages over Ali. Liu Qiangdong replied that JD.COM paid attention to the user experience and only sold genuine products. The host who asked questions gave a "hehehehehehehehehe" laugh. The next day, Hou Enlong released the Weibo, posting six words: "Hehehehehehehehehe", accompanied by a Pinocchio with a long nose in the cartoon Pinocchio.

This year’s "double 11", Suning’s carnival activities will last for 12 days, and the slogan shouted is "Go to the streets and go to Suning". Among them, November 9th is the "Super Store Day", and the offline stores (Su Xiansheng, Suning Store, Suning Plaza, Suning Red Kids, Suning.cn) will deliver it in 30 minutes at the earliest, and pay for it in one hour. Offline stores will also actively push red envelopes for users within 3 kilometers.

In addition, Suning is still promoting offline services. On October 20 this year, Suning opened the first Hakka-helping shop in Nanjing, providing various services needed by life, such as household appliances cleaning, housekeeping cleaning, laundry, home improvement, etc. Consumers in the surrounding area of 3 to 5 kilometers can enjoy the "321" service standard created by helping Hakka, that is, 3 minutes response, 2 hours door-to-door service and 1 hour service completion. At the press conference, Suning also announced that Suning Automobile officially launched the O2O service system. After purchasing the aftermarket products, consumers can directly enjoy the installation and maintenance services offline. At present, the first batch of offline outlets that have settled in Suning Automobile O2O service system have reached 28,000.

It is worth mentioning that on the eve of "double 11" this year, some express delivery companies, including Zhongtong and Yuantong, have announced price increases and allocated parts fees. At the kick-off meeting of Suning Carnival on October 26, Suning announced that from November 1 to 11, Suning’s self-operated products will be free of freight, and consumers don’t have to make up for free freight.

When talking about why the freight rate is not increased, Hou Enlong explained: "First, we are a retail enterprise, not a courier company. It is very immoral for you to be a retail enterprise to increase the freight rate, because you are a retailer and you are not a courier. This is the first. Second, you let all the poor people not come to you. You are doing the rich economy, and you are guilty of pink eye. "

In addition, after Alipay’s "koi fish" campaign became popular, Suning also decided to launch similar marketing measures. From November 1 to 11, Suning.cn will select a "transit lion" every day, and more than 100 brands will contract its consumption demand for one year.